Most people with Parkinson's disease are described as having idiopathic Parkinson's disease (having no specific cause). There are far less common causes of Parkinson's disease including genetic, toxins, head trauma, and drug-induced Parkinson's disease.
Genetic
In recent years, a number of specific genetic mutations causing Parkinson's disease have been discovered, including in certain populations (Contursi, Italy). These account for a small minority of cases of Parkinson's disease. Somebody who has Parkinson's disease is more likely to have relatives that also have Parkinson's disease. However, this does not mean that the disorder has been passed on genetically.
Toxins
One theory holds that the disease may result in many or even most cases from the combination of a genetically determined vulnerability to environmental toxins along with exposure to those toxins. This hypothesis is consistent with the fact that Parkinson's disease is not distributed homogeneously throughout the population: rather, its incidence varies geographically. It would appear that incidence varies by time as well, for although the later stages of untreated PD are distinct and readily recognizable, the disease was not remarked upon until the beginnings of the Industrial Revolution, and not long thereafter become a common observation in clinical practice. The toxins most strongly suspected at present are certain pesticides and transition-series metals such as manganese or iron, especially those that generate reactive oxygen species, and or bind to neuromelanin, as originally suggested by G.C. Cotzias. In the Cancer Prevention Study II Nutrition Cohort, a longitudinal investigation, individuals who were exposed to pesticides had a 70% higher incidence of PD than individuals who were not exposed.
MPTP is used as a model for Parkinson's as it can rapidly induce parkinsonian symptoms in human beings and other animals, of any age. MPTP was notorious for a string of Parkinson's disease cases in California in 1982 when it contaminated the illicit production of the synthetic opiate MPPP. Its toxicity likely comes from generation of reactive oxygen species through tyrosine hydroxylation.
Other toxin-based models employ PCBs, paraquat (a herbicide) in combination with maneb (a fungicide) rotenone (an insecticide), and specific organochlorine pesticides including dieldrin and lindane.Numerous studies have found an increase in PD in persons who consume rural well water; researchers theorize that water consumption is a proxy measure of pesticide exposure. In agreement with this hypothesis are studies which have found a dose-dependent an increase in PD in persons exposed to agricultural chemicals.
Head trauma
Past episodes of head trauma are reported more frequently by sufferers than by others in the population. A methodologically strong recent study found that those who have experienced a head injury are four times more likely to develop Parkinson’s disease than those who have never suffered a head injury. The risk of developing Parkinson’s increases eightfold for patients who have had head trauma requiring hospitalization, and it increases 11-fold for patients who have experienced severe head injury. The authors comment that since head trauma is a rare event, the contribution to PD incidence is slight. They express further concern that their results may be biased by recall, i.e., the PD patients because they reflect upon the causes of their illness, may remember head trauma better than the non-ill control subjects. These limitations were overcome recently by Tanner and colleagues, who found a similar risk of 3.8, with increasing risk associated with more severe injury and hospitalization.
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I was able to overcome senile dementia via a complete naturopathic process.
About two years ago, when I was 56, I started feeling foggy and had occasional memory lapses. My wife, Mary, started to notice it, too, but I also have hearing issues so she thought that was the problem. My memory worsened very gradually over the years, and we lived with it, compensating as needed. I became less social. After some months thereafter, it got to the point where we couldn’t keep making excuses or ignoring it. I had gone from doing our grocery shopping without a list to going with a list, to having the list but not buying what was on it.
Mary went online to do some research, and it was during this process we had been fortunate enough to come across Dr. Utu Herbal Cure: an African herbalist and witch doctor whose professional works had majored on the eradication of certain viral conditions, especially dementia, ( improving the memory capacity positively), via a traditional, naturopathic process and distinguished diet plan. It was by the administration of this herbal specialist that I had been able to improve my condition for better. So to say, the encounter with the above-mentioned herbal practitioner was the first time we ever heard there was something that possibly can be done to improve my memory functionality.
By the existence of such an encounter, I was able to learn of the new approach by which this herbalist successfully treated dementia conditions, which included a distinguished herbal therapy and lifestyle changes of which I had undergone to a tremendous, positive effect.
It was after the completion of the herbal therapy I had started to experience a great deal of cognitive improvement when it came to rational decision making.
In brief, I was able to go through the dreadful hollows of senile dementia without any further hazardous damage to my health condition, and within a short period. Had it not been for the support of my wife, of whom had encouraged me to undergo the above-mentioned therapy and that of the herbal practitioner of whom now happens to be benefactor - I would have been long exposed to the further perils of this condition and of which had been apt to result to a calamitous end.
I would also wish for the same positiveness upon patients who may happen to be suffering from this debilitating disease, and would warmly beseech them to find a confidant like this herbal specialist with whose professional service I was able to attain a divine recovery.
For further information concerning this African traditional cure for Alzheimer's illness; feel free to contact this Dr. Utu directly via email: drutuherbalcure@gmail.com.
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